Introduction of Afanat 40 mg Tablet

• ​Afanat 40 mg Tablet is indicated for the treatment of patients with advanced or metastatic non-squamous non-small cell lung cancer, and Afanat 40 mg Tablet is used as a first-line or follow-up option after failure of cytotoxic chemotherapy. To be eligible for this treatment, tumours must have specific mutations an epidermal growth factor receptor (EGFR) exon 19 deletion or an L858R substitution mutation. This Afanat 40 mg Tablet is not suitable for children or adolescents as its safety and effectiveness in these groups are unknown.
  
  ​Afanat 40 mg Tablet may cause side effects, including diarrhoea, skin rash, and nausea. It may also cause serious side effects, such as liver damage and lung inflammation. It is important to talk to your doctor about any side effects you experience while taking Afanat 40 mg Tablet. Do not use if you have an allergy to Afanat 40 mg Tablet or any of its ingredients.
  
  ​Before taking this Afanat 40 mg Tablet, inform your doctor if you have respiratory problems, liver or kidney issues, or are taking any other medications to treat infections. Other medications may interact with this Afanat 40 mg Tablet, so inform your healthcare team of all medications you are taking. This Afanat 40 mg Tablet is not recommended during pregnancy or while breastfeeding. It is essential for females to use effective contraception during treatment to avoid pregnancy.

  The effectiveness and safety of Afanat 40 mg Tablet have not been confirmed in patients with different forms of EGFR mutations. Afanat 40 mg Tablet has the potential to reduce fertility in both males and females, which may impact your ability to conceive. If this concerns you, it is advisable to consult your doctor for further guidance.
  

Uses of Afanat 40 mg Tablet

• ​​​Non-small cell lung cancer: Afanat 40 mg Tablet is used to treat non-small cell lung cancer, which is a type of lung cancer that affects a large number of cells in the lung. ​​
  

Benefits of Afanat 40 mg Tablet

• ​Afanat 40 mg Tablet inhibits a protein called epidermal growth factor receptor (EGFR), which is involved in the growth and spread of cancer cells. By inhibiting this protein, Afanat 40 mg Tablet can help to slow the progression of cancer.
  
  ​Afanat 40 mg Tablet may be able to help reduce the severity of cancer-related symptoms, such as pain and fatigue, which may improve the patient's overall quality of life.
  
  ​Afanat 40 mg Tablet may be used in combination with other cancer treatments, such as chemotherapy, to improve their effectiveness.​

Side Effects of Afanat 40 mg Tablet

• ​​​​Like all medications, Afanat 40 mg Tablet can cause side effects but do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them.​

Most Common Side Effects of Afanat 40 mg Tablet

• • Decreased appetite
  • Burning sensation during urination
  • Fatigue
  • Ankles and feet swelling.

Common Side Effects of Afanat 40 mg Tablet

• • Vomiting
  • Diarrhoea
  • Mouth sores
  • Acne
  • Itchiness
  • Rashes

How to Use Afanat 40 mg Tablet?

• ​​Afanat 40 mg Tablet should be taken on an empty stomach at least one hour before or two hours after a meal. Always take Afanat 40 mg Tablet exactly as directed by your doctor, including the recommended number and timing of tablets. Do not change your dose or stop this medicine without consulting your doctor. If you miss a dose, take it as soon as possible. If the next dose is scheduled within 12 hours, skip the missed dose and continue with the regular dosing regimen. It is not recommended to take two doses at the same time. If you overdose on Afanat 40 mg Tablet, contact your doctor immediately or seek medical help at the nearest hospital emergency department.​

How Afanat 40 mg Tablet Works?

• ​​Afanat 40 mg Tablet works by inhibiting the activity of the epidermal growth factor receptor (EGFR) protein, which is found on the surface of cells and is involved in the growth and proliferation of cancer cells. When EGFR is activated, it sends signals to the inside of the cell to grow and divide. Afanat 40 mg Tablet binds to the EGFR and prevents it from activating, thereby inhibiting the growth and proliferation of cancer cells.​​

Safety Advices Afanat 40 mg Tablet

Kidney

Use with Caution

Afanat 40 mg Tablet is safe for use in patients with mild to moderate kidney disease, no dose adjustment of Afanat 40 mg Tablet is recommended. The use of Afanat 40 mg Tablet Tablet is not recommended for severe kidney disease patients. It is important to discuss all of your medical conditions and medications with your doctor to ensure that the treatment plan is safe and effective for you.

Alcohol

Unsafe

It is generally not recommended to drink alcohol while taking Afanat 40 mg Tablet. It may increase the risk of liver damage. it is best to avoid alcohol or limit your alcohol consumption while taking any medication.

Breastfeeding

Unsafe

It is not recommended to breastfeed while taking Afanat 40 mg Tablet. Afanat 40 mg Tablet may pass into breast milk and harm the infant. If you are breastfeeding and taking Afanat 40 mg Tablet, it is important to talk to your doctor about the possible risks and benefits of continuing to breastfeed. Your doctor will be able to help you make the best decision for you and your baby's health.

Pregnancy

Unsafe

Use of Afanat 40 mg Tablet may be unsafe during pregnancy as animal studies indicate that it may harm the developing foetus. However, if you are pregnant or planning to become pregnant, it is important to talk to your doctor about the potential risks and benefits of taking Afanat 40 mg Tablet during pregnancy. Your doctor will be able to help you make the best decision for you and your baby's health.

Driving

Unsafe

Afanat 40 mg Tablet may cause dizziness, fatigue, and difficulty concentrating and coordinating, which may affect your ability to drive a vehicle safely. It is important to follow your doctor's instructions and take necessary precautions such as avoiding driving a vehicle or operating heavy machinery if you suffer from the side effects of this Afanat 40 mg Tablet.

Liver

Use with Caution

Afanat 40 mg Tablet is safe for use in patients with mild to moderate liver disease, no dose adjustment of Afanat 40 mg Tablet is recommended. The use of Afanat 40 mg Tablet is not recommended for severe liver disease patients. It is important to discuss all of your medical conditions and medications with your doctor to ensure that the treatment plan is safe and effective for you.