Introduction of Darzalex 400 mg Injection

• ​Darzalex 400 mg Injection is an anticancer medicine used alone or combination with other medicines to treat certain types of cancers, especially multiple myeloma (Multiple myeloma is a type of cancer that affects plasma cells, which are a type of white blood cells involved in the immune system). Darzalex 400 mg Injection can decrease platelets (helps in blood clotting) and white blood cell counts (helps fight infections).
  
  ​Darzalex 400 mg Injection may cause some common adverse effects including, injection site reactions such as fever, chills, itching, rash, headache, dizziness, nausea, and difficulty breathing. These reactions typically occur during or shortly after the infusion and can range from mild to severe. Darzalex 400 mg Injection may reduce the number of blood cells (decrease white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells while taking this medicine.
  
  ​Before taking Darzalex 400 mg Injection, inform your doctor if you are suffering any healthcare-related problems like neutropenia/thrombocytopenia, liver disease and kidney disease or any other problems. You may also inform if you are taking any prescription medicines or vitamins, or herbal medicines. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. Darzalex 400 mg Injection is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
  
  ​Darzalex 400 mg Injection is usually given as an injection into the vein under the supervision of a doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.​
  

Uses of Darzalex 400 mg Injection

• ​​Multiple Myeloma (plasma cell myeloma): Darzalex 400 mg Injection is used to treat multiple myeloma a type of cancer that affects plasma cells, which are a type of white blood cell that produce antibodies. In multiple myeloma, abnormal plasma cells accumulate in the bone marrow and interfere with the production of normal blood cells. Symptoms of multiple myeloma can include bone pain, weakness and fatigue, recurrent infections, anaemia, and kidney damage.​
  

Benefits of Darzalex 400 mg Injection

• ​Darzalex 400 mg Injection is prescribed in multiple myeloma. In multiple myeloma, bones become weak and destroy factor and these weak bones are painful and prove to break. Darzalex 400 mg will kill the cancerous cells and prevent their further growth as well as spread to other parts of the body. Follow your doctor’s instructions carefully to get the most benefit. Supplements of calcium and Vitamin D3 are also effective and may be prescribed if you do not have high blood calcium levels.​

Side Effects of Darzalex 400 mg Injection

• ​Like all medications, Darzalex 400 mg Injection may have side effects, although not everyone will experience them.​

Most Common Side Effects of Darzalex 400 mg Injection

• • Itching
  • Rashes
  • Backpain
  • constipation
  • Diarrhoea
  • Dizziness
  • Fatigue
  • Fever
  • low blood counts ( like platelet count)
  • Joint pain
  • Breathlessness
  • Vomiting
  • URTI ( upper respiratory tract infection)
  • Nasal congestion
  • Throat irritation
  • High blood pressure

Common Side Effects of Darzalex 400 mg Injection

• • Respiratory distress (like shortness of breaths, rapid breathing)
  • Wheezing
  • High or low blood pressure
  • ​Chest tightness
  • Facial swelling
  • Lymphopenia
  • Neutropenia
  • Thrombocytopenia
  • Anemia
    

How to Use Darzalex 400 mg Injection?

• Darzalex 400 mg Injection is administered as an intravenous drug. (as an IV infusion ). Duration of infusion may be shorter or prolonged which is depending upon your body reactions. Your doctor will decide about the dosage and duration. Darzalex 400 mg Injection is available only in injectable form, No oral pill is available for this drug.

How Darzalex 400 mg Injection Works?

• ​Darzalex 400 mg Injection is a monoclonal antibodies, which are designed to recognise and attach to specific proteins on the surface of cancer cells. It shows its action by binding to specific cancer cells in the body and helps your immune system kills cancer.​
  

Safety Advices Darzalex 400 mg Injection

Pregnancy

Unsafe

Animal reproduction studies have not been conducted with Darzalex 400 mg Injection.Darzalex 400 mg Injection generally consider unsafe during pregnancy. If you are pregnant or planning to become pregnant, it is important to talk to your doctor about the potential risks and benefits of taking Darzalex 400 mg during pregnancy. Your doctor will be able to help you make the best decision for you and your baby's health.

Breastfeeding

Unsafe

It is unknown whether Darzalex 400 mg is excreted in human milk. If you are breastfeeding and taking this medicine. It is important to talk to your doctor about the possible risks and benefits of continuing to breastfeed. Your doctor will be able to help you make the best decision for your and your baby's health.

Driving

Safe

Darzalex 400 mg Injection will not affect your ability to drive or operate machinery. In case you experience any side effects while taking Darzalex 400 mg such as dizziness or drowsiness, it is important to avoid driving or operating heavy machinery until the side effects have resolved.

Liver

Use with Caution

Darzalex 400 mg Injection should be used with caution in patients with liver disease. It is important that patients with liver disease closely monitor liver function while taking Darzalex 400 mg and report any unusual symptoms or changes in liver function to their doctor. Your doctor may need to be adjusted the dose in such liver disease patients.

Kidney

Use with Caution

Darzalex 400 mg Injection should be used with caution in patients with kidney disease. It is important that patients with kidney disease closely monitor kidney function while taking Darzalex 400 mg and report any unusual symptoms or changes in kidney function to their doctor. Your doctor may need to be adjusted the dose in such kidney disease patients.

Alcohol

Unsafe

Consumption of alcohol is not recommended while using Darzalex 400 mg Injection. Alcohol may increase or decrease the effectiveness of the medicine and also increase the risk of side effects. It is the best advice for you before consuming alcohol, you can talk with a doctor or pharmacist, and they will tell you consumption of alcohol is safe or not.