


Imatib 400 mg Tablet | 10 Tablets in 1 strip

- Manufacturer/Marketed By
Cipla Ltd
- Active Pharmaceutical Ingredient
Imatinib 400 mg
(Inclusive of all taxes)
Introduction of Imatib 400 mg Tablet
Imatib 400 mg Tablet is an anticancer medicine used to treat certain types of leukaemia (cancer that develops inside the white blood cells) and different cancers and problems of the blood cells. Imatib Tablet is also used to treat certain types of gastrointestinal stromal tumours (GIST, a type of tumour that grows in the walls of the digestive tract and can spread to other parts of the body). Imatib 400 mg is also used to treat protuberant (a tumour that forms under the top layer of skin) when the tumour cannot be surgically removed, has spread to other parts of the body, or has recurred after surgery. Imatib Tablet belongs to a class of drugs called kinase inhibitors. It works by blocking the movement of the strange protein that causes most cancer cells to multiply. This permits to prevention of the spread of maximum cancer cells.
Imatib 400 mg Tablet may cause some common adverse effects including nausea, vomiting, oedema, fatigue, muscle cramps, musculoskeletal pain, diarrhoea, rash, and abdominal pain. Most of these side effects do now not require medical hobby and will clear up steadily over time. However, you're cautioned to speak for your health practitioner in case you revel in those aspect outcomes persistently.
This medicine is used with caution in patients with liver disease or heart-related problems. Imatib Tablet may decrease the blood cell count in the body, and you may get an infection or bleed more easily. If you experience any symptoms like unusual bruising or bleeding, signs of infection (fever, chills, body aches), etc., please consult your doctor.
Before taking Imatib 400 mg Tablet, inform your doctor about past and present health-related problems, if you have any liver or kidney disease, bleeding problems, diabetes, any stomach ulcers, thyroid-related problems, or are taking other medications to treat infections. Other medications may interact with this Imatib 400 mg Tablet, so inform your healthcare team of all your medications. This Imatib Tablet is not recommended during pregnancy or while breastfeeding. Females need to use effective contraception during treatment to avoid pregnancy.
Imatib 400 mg Tablet can be taken with food or as directed by your doctor. It is best to take the same time daily to improve the clinical condition. If you miss a dose of Imatib 400 mg take your next dose at your regularly scheduled time. The dose and length of treatment will depend on your condition. Do not stop taking this medicine without consulting your doctor.
Uses of Imatib 400 mg Tablet
Chronic Myelogenous Leukemia: Imatib 400 mg Tablet is used in the treatment of Chronic myelogenous leukaemia (CML), also known as chronic myeloid leukaemia, which is a type of cancer that affects the blood-forming cells in the bone marrow and the blood cells in the body.
Acute Lymphoblastic Leukemia: Imatib Tablet is used in the treatment of Acute lymphoblastic leukaemia (ALL) a type of cancer that affects the blood-forming cells in the bone marrow and the blood cells in the body. It is characterized by the production of too many immature white blood cells, called lymphoblasts, which are not able to function properly.
Myeloproliferative Disorder: Imatib 400 mg is used in the treatment of Myeloproliferative disorders are a group of blood disorders that affect the bone marrow and the blood cells in the body. They are characterized by the uncontrolled production of blood cells, which can lead to an overabundance of red blood cells, white blood cells, or platelets.
Myelodysplastic Disease Syndrome(MDS): Imatib 400 mg Tablet is used in the treatment of the Myelodysplastic syndrome group of blood disorders that affect the bone marrow and the blood cells in the body. It is characterized by the production of abnormal blood cells that do not function properly, leading to a deficiency of red blood cells, white blood cells, and platelets.
Systemic Mastocytosis: Imatib 400 mg Tablet is used in the treatment of Systemic Mastocytosis a rare type of cancer that affects the body's mast cells, which are a type of white blood cell involved in the immune system. In people with systemic mastocytosis, there is an excessive number of mast cells in the body, which can lead to a variety of symptoms and complications.
Hypereosinophilic Syndrome (HES): Imatib Tablet is used in the treatment of Hypereosinophilic syndrome is a rare disorder that is characterized by an excess of eosinophils, a type of white blood cell, in the body. Eosinophils play a role in the immune system and are involved in fighting infections and allergies.
Chronic Eosinophilic Leukemia(CEL): Imatib 400 mg Tablet is used in the treatment of Chronic eosinophilic leukaemia, which is a rare type of cancer that affects the blood-forming cells in the bone marrow and the blood cells in the body.
Dermatofibrosarcoma Protuberans(DFSP): Imatib 400 mg is used in the treatment of Dermatofibrosarcoma protuberans is a rare type of cancer that affects the skin and the tissue beneath the skin. It typically begins as a small, firm lump or bump on the skin and can grow slowly over time.
Benefits of Imatib 400 mg Tablet
Imatib 400 mg Tablet helps to reduce the size of cancerous tumours and slow the growth of cancer cells.
Imatib Tablet can be used as part of a treatment plan to help increase the chances of remission or cure in patients with certain types of cancer.
Imatib 400 mg Tablet can help to reduce the number and severity of cancer-related symptoms, such as fatigue, pain, and nausea.
Imatib 400 mg Tablet can be taken orally, which makes it easier for patients to take the medication and Imatib 400 mg Tablet has relatively few side effects compared to other cancer treatments, such as chemotherapy.
Side Effects of Imatib 400 mg Tablet
Adverse reactions may occur with the use of Imatib 400 mg Tablet. Should you notice any of these side effects, it is advisable to consult your doctor or healthcare professional without delay. Your doctor can offer guidance on managing or alleviating these side effects.
Most Common Side Effects of Imatib 400 mg Tablet
- Nausea
- Vomiting
- Joint Pain
- Bone pain
- Muscle Cramps
- Sweating
- Watery Eyes
- Pink Eyes
- Flushing
- Itching
- Hair loss
Common Side Effects of Imatib 400 mg Tablet
- Shortness Of Breath
- Irregular Heartbeats
- Chest Pain
- Blistered skin
- Blood in Stool
- Severe Abdominal Pain and Bloating
- Blood in sputum
- High Fever
- Intestinal Bleeding
- Hepatic problems
- Diarrhea
- Dry mouth
- Loss of appetite
- Weight loss
- Headache
- Nail Color Changes
- Chills
- Sore throat
- Frequent Urination
- Tiredness
How to Use Imatib 400 mg Tablet?
Imatib 400 mg Tablet can be taken with food or as directed by your doctor. It is best to take the same time daily to improve the clinical condition. If you miss a dose of Imatib 400 mg Tablet take your next dose at your regularly scheduled time. The dose and duration of remedy will depend upon your condition. Do not stop taking this medicine without consulting your doctor.
How Imatib 400 mg Tablet Works?
Imatib 400 mg Tablet works by inhibiting the activity of specific proteins called tyrosine kinases, which are involved in the growth and proliferation of cancer cells. When these proteins are blocked, cancer cells are unable to grow and divide, which can help to slow the progression of cancer.
Safety Advices Imatib 400 mg Tablet

Alcohol
Unsafe
The consumption of alcohol is generally not recommended when using Imatib Tablet due to the increased risk of liver damage. It is best to either avoid alcohol altogether or limit its consumption while undergoing any medication.

Liver
Use with Caution
Patients with liver disease should exercise caution when using Imatib 400 mg Tablet. It is crucial for individuals with liver disease to closely observe their liver function while using Imatib 400 mg Tablet and promptly inform their physician of any abnormal symptoms or changes in liver function. Adjustments to the dosage of Imatib 400 mg Tablet may be necessary for patients with liver disease.

Kidney
Use with Caution
Imatib Tablet should be used with mild kidney disease patients (CrCl 40 to <60 mL/min): Doses >600 mg/day are not recommended and moderate kidney patients (CrCl 20 to <40 mL/min): Decrease dose by 50%; may increase future doses if tolerated. Imatib 400 mg Tablet used in caution patients with severe kidney disease take 100-mg/day dose was tolerated.

Breastfeeding
Unsafe
The excretion of Imatib Tablet in human milk is currently unknown. Considering that various drugs, including other anthracyclines, are excreted in human milk and the possibility of severe adverse reactions in nursing infants from Imatib 400 mg Tablet, it is recommended that lactating women refrain from breastfeeding while undergoing treatment with Imatib Tablet and for a minimum of 7 days after the final dose.

Driving
Unsafe
Your doctor's instructions should be strictly followed, especially if you encounter any side effects from Imatib 400 mg Tablet. These side effects, such as dizziness, fatigue, and difficulty concentrating and coordinating, have the potential to hinder your capability to drive a vehicle safely. Taking necessary precautions, such as refraining from driving or operating heavy machinery, is essential to ensure your well-being while using Imatib Tablet.

Pregnancy
Unsafe
The use of Imatib 400 mg Tablet during pregnancy may not be safe, as indicated by animal studies that suggest potential harm to the developing foetus. However, if you are currently pregnant or planning to become pregnant, it is crucial to consult your doctor about the potential risks and benefits of using Imatib 400 mg Tablet during pregnancy. Your doctor will be able to assist you in making the most appropriate decision for the health and well-being of both you and your baby.
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