Introduction of Kadcyla 160 mg Injection

• Kadcyla 160 mg Injection is used to treat certain types of breast cancer. It is used to treat tumours that produce more than the normal amount of a certain substance called HER2 protein.  Kadcyla 160 mg Injection is called a monoclonal antibody and the microtubule inhibitor conjugate. Kadcyla 160 mg Injection works by attaching to the HER2 cancer cells and blocking them from dividing and growing. It may also destroy the cancer cells or signal the body (immune system) to destroy the cancer cells.

  Kadcyla 160 mg Injection may cause some common adverse effects including liver changes, bruising, bleeding gums or nose bleeds, numbness or tingling in fingers or toes, breathlessness and looking pale, feeling or being sick, diarrhoea or constipation, dry mouth, urinary tract infections (UTIs), difficulty sleeping, headaches, tummy (abdominal) cramps, cough and difficulty breathing, sore mouth, Joint or muscle pain, tiredness and weakness, high temperature (fever), etc. Kadcyla 160 mg Injection may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels.

  Before taking Kadcyla 160 mg Injection, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. Kadcyla 160 mg Injection is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

  Kadcyla 160 mg Injection is given as an injection by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Uses of Kadcyla 160 mg Injection

• • Early Breast Cancer (EBC)
    
  • Metastatic Breast Cancer (MBC)

Benefits of Kadcyla 160 mg Injection

• Early Breast cancer: Kadcyla 160 mg Injection helps to treat initial stages of breast cancer and it may be used alone or in combination with other medicines or treatment modalities like chemotherapy. It relieves the symptoms of breast cancer such as breast lumps, bloody discharge from nipples or changes in the shape or texture of the breast. Kadcyla 160 mg Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. Discuss with your doctor if any of the side effects bother you.

  Metastatic breast cancer: Kadcyla 160 mg Injection helps to treat breast cancer and it may be used alone or in combination with other medicines or treatment modalities like chemotherapy. This medicine is used when other medicines have not shown significant improvement and cancer has spread to other parts as well. It relieves the symptoms of breast cancer such as breast lumps, bloody discharge from nipples or changes in the shape or texture of the breast. Kadcyla 160 mg kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. Discuss with your doctor if any of the side effects bother you.

Side Effects of Kadcyla 160 mg Injection

• ​​​​​​Like all medication, Kadcyla 160 mg Injection may cause some side effects. If you experience any of these side effects contact your doctor as soon as possible. Your doctor may be able to suggest ways to manage or reduce the severity of these side effects.​​​​
  

Most Common Side Effects of Kadcyla 160 mg Injection

• • Decrease platelet count
  • Nausea
  • Decrease red blood cells
  • Decrease white blood cells
  • Increased liver enzymes
  • Decrease potassium
  • Musculoskeletal Pain
  • Fatigue
  • ​Headache
  • Diarrhea
  • Constipation
  • Vomiting
  • Fever
  • Abdominal pain
  • Cough
  • Peripheral neuropathy
  • Weakness
  • Mouth sores
  • Nose bleeds
  • Dry mouth
  • Insomnia (Trouble in sleeping)
  • Rash
  • Dizziness
  • Shortness of breath
  • Constipation
  • Increase bilirubin​
    

Common Side Effects of Kadcyla 160 mg Injection

• • Yellowing of the skin or eyes
  • Dark Urine or bloody or black, tarry stools
  • Body Infections signs: Chills, Fever, ear or sinus pain, very bad sore throat, difficulty urinating, cough without or with spatum, wounds that will not heal.
  • Rightside abdominal pain
  • Bloody vomiting
  • Difficulty in swallowing or breathing
  • Nosebleeds

How to Use Kadcyla 160 mg Injection?

• Kadcyla 160 mg Injection is in power form to be mixed it with liuid and slowly injected (infused) into a body vein by a health care professional, doctor or nurse in a medical facility or hospital. The dosage schedule depends on your how well your body reacts to the medication and side effect of the medication you experience. Dosage and frequency will be decided by your doctor, If you experience any serious side effect, inform your doctor immediately.

How Kadcyla 160 mg Injection Works?

• Kadcyla 160 mg Injection is a monoclonal antibody (mAb or moAb) that target cell surface (HER2) human epidermal growth factor receptor 2 on the cancer cell, Interfering RNA leads to apoptotic cell death. Kadcyla 160 mg Injection (T-DM1) is an antibody–drug conjugate that incorporates HER2 targeted antitumor properties of trastuzumab covalently linked to a microtubule inhibitor (DM1, a maytansine derivative).

Safety Advices Kadcyla 160 mg Injection

Liver

Use with Caution

If you suffering from liver disease, please consult the doctor before taking Kadcyla 160 mg Injection. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

Alcohol

Unsafe

It is not recommended to consume alcohol while taking Kadcyla 160 mg Injection. Alcohol may increase the risk of side effects or interfere with the effectiveness of the Kadcyla 160 mg. It is best to talk to your doctor or pharmacist before consuming alcohol while taking any medicine.

Pregnancy

Unsafe

Use of Kadcyla 160 mg Injection may be unsafe during pregnancy as animal studies indicate that it may harm the developing foetus. However, if you are pregnant or planning to become pregnant, it is important to talk to your doctor about the potential risks and benefits of taking Kadcyla 160 mg during pregnancy. Your doctor will be able to help you make the best decision for you and your baby's health.

Breastfeeding

Unsafe

It is not recommended to breastfeed while taking Kadcyla 160 mg. Kadcyla 160 mg Injection may pass into breast milk and harm the infant. If you are breastfeeding and taking Kadcyla 160 mg, it is important to talk to your doctor about the possible risks and benefits of continuing to breastfeed. Your doctor will be able to help you make the best decision for you and your baby's health.

Kidney

Use with Caution

If you suffering from kidney disease, please consult the doctor before taking Kadcyla 160 mg Injection. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

Driving

Use with Caution

Kadcyla 160 mg Injection may cause dizziness, fatigue, and difficulty concentrating and coordinating, which may affect your ability to drive a vehicle safely. It is important to follow your doctor's instructions and take necessary precautions such as avoiding driving a vehicle or operating heavy machinery if you suffer from the side effects of this Kadcyla 160 mg.