Introduction of Metodox 50 mg Injection

• Metodox 50 mg Injection is used with other medicines to treat certain types of bladder, breast, lung, stomach, and ovarian cancer, Hodgkin's lymphoma (Hodgkin's disease) and non-Hodgkin's lymphoma (cancer that originates in the cells of the immune system), and certain types of leukaemia (cancer of the white blood cells), including acute lymphocytic leukaemia (ALL) and acute myeloid leukaemia (AML). Metodox 50 mg Injection is also used alone or in combination with other medicines to treat certain types of thyroid cancer and certain types of soft tissue or bone sarcoma (cancer that forms in muscles and bones). It is also used to treat neuroblastoma (cancer that starts in nerve cells and occurs mainly in children) and Wilms tumour (a type of kidney cancer that occurs in children). Metodox 50 mg Injection belongs to a class of drugs called anthracyclines. It works by slowing or stopping the growth of cancer cells in your body.
  
  Metodox 50 mg Injection may cause some adverse effects including vomiting, allergic reaction, nausea, mouth soreness, and hair loss. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. This medicine may reduce the number of blood cells in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells. It is important to talk to your doctor about the potential risks and benefits of taking Metodox 50 mg Injection. Inform your doctor if you notice unusual bleeding or bruising, lack of energy, loss of appetite, and yellowing of eyes. Your doctor will advise you regular blood tests to check for these.
  
  Before taking Metodox 50 mg Injection, inform your doctor about your past and present medical history, if you have any pre-existing disease such as liver and kidney or blood disorders, any infections or any other medical complications. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. Metodox 50 mg Injection is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
  
  ​​​​Metodox 50 mg Injection is administered intravenously at a hospital or clinic setting by a doctor or nurse. Your doctor will decide the right time to take the injection, so always follow your doctor's advice. The dose and how often you take it depends on what you are taking it for. You might be prescribed certain other medicine as a part of your treatment. You should take this medicine for as long as it is prescribed for you.​
  
  Metodox 50 mg Injection should not be used in patients with severe liver disease, severe heart problems, very low blood cell counts caused by prior chemotherapy, or if you recently had a heart attack.
  

Uses of Metodox 50 mg Injection

• Breast cancer: Metodox 50 mg Injection is used to treat Breast cancer is a type of cancer that affects the cells in the breast tissue. It is the second most common type of cancer in women and is often characterized by the presence of a tumour or lump in the breast.
  
  Bladder cancer: Metodox 50 mg Injection is used in the treatment of Bladder cancer is a type of cancer that affects the bladder, which is a muscular organ in the lower abdomen that stores urine. It is most common in men over the age of 50 and is usually found in the cells lining the inside of the bladder.
  
  Kaposi's sarcoma: Metodox 50 mg Injection is used in the treatment of Kaposi's sarcoma is a type of cancer that can affect the skin, mouth, and internal organs. It is caused by a virus called human herpesvirus 8 (HHV-8), which is also known as Kaposi's sarcoma-associated herpesvirus (KSHV). Kaposi's sarcoma is more common in people with compromised immune systems, such as people with HIV/AIDS or organ transplant recipients taking immunosuppressive drugs.
  
  Hodgkin's lymphoma: Metodox 50 mg Injection is used in the treatment of Hodgkin's lymphoma, also known as Hodgkin's disease, which is a type of cancer that affects the lymphatic system.
  
  Acute lymphocytic leukaemia(ALL): Metodox 50 mg Injection is used in the treatment of Acute lymphocytic leukaemia a type of cancer that affects the blood and bone marrow.
  
  

Benefits of Metodox 50 mg Injection

• Metodox 50 mg Injection may help to treat certain kinds of cancer. It may be used alone or in combination with other medicines to treat cancer in various parts of the body. Metodox 50 mg Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.
  

Side Effects of Metodox 50 mg Injection

• Metodox 50 mg Injection may cause some side effects. If you experience any of these side effects contact your doctor as soon as possible. Your doctor may be able to suggest ways to manage or reduce the severity of these side effects.

Most Common Side Effects of Metodox 50 mg Injection

• • Injection site reactions
  • Hair loss
  • Bone marrow suppression
  • Vomiting
  • Rash
  • Inflammation of the mouth
    

Common Side Effects of Metodox 50 mg Injection

• • Allergic reactions
  • Heart damage
  • Tissue damage at the site of injection
    

How to Use Metodox 50 mg Injection?

• Metodox 50 mg Injection is given intravenously (IV), administered by a healthcare professional in a hospital or clinic setting. The specific dosing and administration of this medicine will depend on the clinical condition of the patient's age and medical history and other factors. It is important to follow your doctor's instructions carefully when using this medication. Do not self-administered.
  

How Metodox 50 mg Injection Works?

• Metodox 50 mg Injection interacts with DNA by inhibition and the intercalation of the macromolecular biosynthesis. Metodox 50 mg Injection stabilizes the topoisomerase II complex after it breaks the chain of the DNA needed for replication. Metodox 50 mg prevents the double helix DNA to get sealed and it gradually stops the replication process. Metodox 50 mg may also increase quinone-type free radical production, hence contributing to its cytotoxicity.
  

Safety Advices Metodox 50 mg Injection

Alcohol

Unsafe

It is generally not recommended to drink alcohol while taking Metodox 50 mg Injection. It may increase the risk of liver damage. it is best to avoid alcohol or limit your alcohol consumption while taking any medication.

Driving

Unsafe

Metodox 50 mg Injection may cause dizziness, fatigue, and difficulty concentrating and coordinating, which may affect your ability to drive a vehicle safely. It is important to follow your doctor's instructions and take necessary precautions such as avoiding driving a vehicle or operating heavy machinery if you suffer from the side effects of this Side effects of Metodox 50 mg Injection.

Kidney

Safe

Metodox 50 mg Injection is safe to use in patients with kidney disease. No dose adjustment of Metodox 50 mg Injection is recommended. If you experience any side effects please consult your doctor.

Pregnancy

Unsafe

Use of Metodox 50 mg Injection may be unsafe during pregnancy as animal studies indicate that it may harm the developing foetus. However, if you are pregnant or planning to become pregnant, it is important to talk to your doctor about the potential risks and benefits of taking Metodox 50 mg Injection during pregnancy. Your doctor will be able to help you make the best decision for you and your baby's health.

Liver

Use with Caution

Metodox 50 mg Injection should be used with caution in patients with liver disease. It is important that patients with liver disease closely monitor liver function while taking Metodox 50 mg and report any unusual symptoms or changes in liver function to their doctor. The dose of Metodox 50 mg may need to be adjusted in patients with liver disease.

Breastfeeding

Unsafe

It is not recommended to breastfeed while taking Metodox 50 mg. Metodox 50 mg Injection may pass into breast milk and harm the infant. If you are breastfeeding and taking Metodox 50 mg, it is important to talk to your doctor about the possible risks and benefits of continuing to breastfeed. Your doctor will be able to help you make the best decision for you and your baby's health.