Introduction of Pegadria 50 mg Injection

• ​Pegadria 50 mg Injection is an anthracycline topoisomerase inhibitor. It is used for some kinds of cancers such as ovarian cancer, Breast cancer, and AIDS-related Kaposi’s Sarcoma. It may be used with other medicines to treat Multiple Myeloma (Multiple myeloma is cancer that forms in a type of white blood cell called a plasma cell). Pegadria 50 mg Injection belongs to a class of drugs called anthracyclines. It works by slowing or stopping the growth of cancer cells in your body.   Pegadria 50 mg Injection is not recommended in patients under 18 years of age.
  
  ​Pegadria 50 mg Injection may cause some adverse effects including vomiting, allergic reaction, nausea, mouth soreness, and hair loss. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. Pegadria 50 mg Injection may reduce the number of blood cells in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells. It is important to talk to your doctor about the potential risks and benefits of taking Pegadria 50 mg Injection. Inform your doctor if you notice unusual bleeding or bruising, lack of energy, loss of appetite, and yellowing of eyes. Your doctor will advise you regular blood tests to check for these.
  
  ​​Before taking Pegadria 50 mg Injection, inform your doctor about your past and present medical history, if you have any pre-existing disease such as liver and kidney or blood disorders, any infections or any other medical complications. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. Pegadria 50 mg Injection is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
  
  ​Pegadria 50 mg Injection is administered intravenously at a hospital or clinic by a doctor or nurse. Your doctor will decide the right time to take the injection, so always follow your doctor's advice. The dose and how often you take it depends on what you take it for. You might be prescribed particular other medicine as a part of your treatment. You should take Pegadria 50 mg Injection as long as it is prescribed for you.​
  

Uses of Pegadria 50 mg Injection

• • Breast cancer
  • Bladder cancer
  • Kaposi's sarcoma
  • Hodgkin's lymphoma
  • Acute lymphocytic leukaemia

Benefits of Pegadria 50 mg Injection

• ​​Pegadria 50 mg Injection may help to treat certain kinds of cancer. It may be used alone or in combination with other medicines to treat cancer in various parts of the body. Pegadria 50 mg Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.​​​

Side Effects of Pegadria 50 mg Injection

• ​​​Pegadria 50 mg Injection may cause some side effects. If you experience any of these side effects contact your doctor as soon as possible. Your doctor may be able to suggest ways to manage or reduce the severity of these side effects.​​​
  

Most Common Side Effects of Pegadria 50 mg Injection

• • Hair loss
  • Bone marrow suppression
  • Vomiting
  • Rash
  • Inflammation of the mouth.

Common Side Effects of Pegadria 50 mg Injection

• • Allergic reactions such as anaphylaxis
  • Heart damage
  • Tissue damage at the site of injection
  • Radiation recall

How to Use Pegadria 50 mg Injection?

• ​​​Pegadria 50 mg Injection is given intravenously (IV), administered by a healthcare professional in a hospital or clinic setting. The specific dosing and administration of this medicine will depend on the clinical condition of the patient's age and medical history and other factors. Following your doctor's instructions carefully when using this medication is important. Do not self-administered.​​​

How Pegadria 50 mg Injection Works?

• ​Pegadria 50 mg Injection interacts with DNA by inhibition and the intercalation of the macromolecule biosynthesis. Pegadria 50 mg Injection stabilizes the topoisomerase II complex after it breaks the chain of the SNA needed for replication. Pegadria 50 mg Injection prevents the double helix DNA to get sealed and it gradually stops the replication process.  Pegadria 50 mg Injection may also increase common-type free radical production, hence contributing to its cytotoxicity.​

Safety Advices Pegadria 50 mg Injection

Liver

Use with Caution

Pegadria 50 mg Injection should be used with caution in patients with liver disease. It is important that patients with liver disease closely monitor liver function while taking Pegadria 50 mg and report any unusual symptoms or changes in liver function to their doctor. The dose of Pegadria 50 mg may need to be adjusted in patients with liver disease.

Kidney

Safe

Pegadria 50 mg Injection is safe to use in patients with kidney disease. No dose adjustment of Pegadria 50 mg Injection is recommended. If you experience any side effects please consult your doctor.

Alcohol

Unsafe

It is generally not recommended to drink alcohol while taking Pegadria 50 mg Injection. It may increase the risk of liver damage. it is best to avoid alcohol or limit your alcohol consumption while taking any medication.

Driving

Unsafe

Pegadria 50 mg may cause dizziness, fatigue, and difficulty concentrating and coordinating, which may affect your ability to drive a vehicle safely. It is important to follow your doctor's instructions and take necessary precautions such as avoiding driving a vehicle or operating heavy machinery if you suffer from the side effects of this Pegadria 50 mg.

Breastfeeding

Unsafe

It is not recommended to breastfeed while taking Pegadria 50 mg. Pegadria 50 mg Injection may pass into breast milk and harm the infant. If you are breastfeeding and taking Pegadria 50 mg, it is important to talk to your doctor about the possible risks and benefits of continuing to breastfeed. Your doctor will be able to help you make the best decision for you and your baby's health.

Pregnancy

Unsafe

Use of Pegadria 50 mg Injection may be unsafe during pregnancy as animal studies indicate that it may harm the developing fetus. However, if you are pregnant or planning to become pregnant, it is important to talk to your doctor about the potential risks and benefits of taking Pegadria 50 mg Injection during pregnancy. Your doctor will be able to help you make the best decision for you and your baby's health.