Introduction of Spegra Tablet 90N

• Spegra Tablet 90N is a combination of antiretroviral medicines containing dolutegravir, emtricitabine, and tenofovir alafenamide. Spegra Tablet 90N is used in the treatment of adults and adolescents (aged 12 years and older with a body weight of at least 40 kg) infected with the Human Immunodeficiency Virus type-1. It also helps to control HIV infection and prevent the development of acquired immunodeficiency syndrome (AIDS).
  
  Spegra Tablet 90N does not completely cure HIV Infection. It will reduce the progression of a chronic potentially life-threatening condition known as acquired immunodeficiency syndrome (AIDS) and other HIV-related conditions. It will work by stopping the virus from multiplying in the body.
  
  Before taking Spegra Tablet 90N talk to your doctor about the potential risks and benefits of taking this medication, as well as any other questions or concerns you may have and also important to let your doctor know if you have any pre-existing diseases or are using any medications, vitamins, supplements, or herbal medicine you are taking.
  
  Spegra Tablet 90N should be taken with or without food daily. It is important to follow your doctor's instructions for taking this medicine and to continue taking the medication as prescribed even if you feel well. Do not stop taking this tablet or change your dosage without first consulting your doctor.
  

Uses of Spegra Tablet 90N

• ​​Human Immunodeficiency Virus Infection (HIV): Spegra Tablet 90N medicine is used in the treatment of human immunodeficiency (HIV) virus infection that attacks and weakens the immune system. It is spread through contact with certain bodily fluids, such as blood, semen, vaginal fluids, and breast milk, from an infected person.​
  

Benefits of Spegra Tablet 90N

• The main benefit of taking Spegra Tablet 90N helps to reduce the amount of HIV virus in the blood (viral load) and improve immune function and also helps to reduce the progression of HIV infection and reduce the risk of developing complications, such as AIDS.
  
  Taking Spegra Tablet 90N has a low risk of side effects compared to some other HIV medications. It is also easy to take, as it only needs to be taken once daily with food.
  
  Spegra Tablet 90N can help reduce the risk of transmitting HIV to others. This can help suppress the virus and reduce the amount of HIV in the body.
  

Side Effects of Spegra Tablet 90N

• ​Spegra Tablet 90N may cause some side effects. If you experience any of these side effects, contact your doctor as soon as possible. Your doctor may be able to suggest ways to manage or reduce the severity of these side effects.
  

Most Common Side Effects of Spegra Tablet 90N

• • Headache
  • Cough
  • Back Pain
  • Cough
  • Fatigue
  • Insomnia
    

Common Side Effects of Spegra Tablet 90N

• • Depression
  • Skin Rashes
  • Nightmares
    

How to Use Spegra Tablet 90N?

• Spegra Tablet 90N should be taken with a full glass of water. You can take it with or without food. Take this medicine exactly as prescribed by your doctor. Do not take more or less of the medication than directed. Do not crush, chew, or break it. If you miss a dose of this medicine, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and take your next dose at the regular time. Do not take two doses at the same time to make up for a missed dose.
  

How Spegra Tablet 90N Works?

• Spegra Tablet 90N contains dolutegravir, emtricitabine, and tenofovir alafenamide. Dolutegravir is an HIV-1 integrase strand transfer inhibitor that blocks an enzyme called integrase, which HIV needs to replicate and spread in the body. Emtricitabine is a nucleoside reverse transcriptase inhibitor (NRTI) that blocks an enzyme called reverse transcriptase, which HIV needs to replicate and spread in the body. Tenofovir alafenamide is also an NRTI that works in a similar way to emtricitabine. Overall, Spegra Tablet works to suppress the HIV virus and reduce the amount of HIV in the body, known as the "viral load." This can help to improve immune function and prevent the progression of HIV to AIDS (acquired immunodeficiency syndrome).​
  

Safety Advices Spegra Tablet 90N

Alcohol

Unsafe

It is generally not recommended to drink alcohol while taking Spegra Tablet 90N. It may increase the risk of liver damage. It is best to avoid alcohol or limit your alcohol consumption while taking any medication.

Driving

Unsafe

Spegra Tablet 90N may cause dizziness, fatigue and sleepiness, which may affect your ability to drive or operate machinery. If you experience any side effects while taking this tablet such as dizziness or sleepiness, it is important to avoid driving or operating heavy machinery until the side effects have resolved.

Liver

Unsafe

Spegra Tablet is not recommended for use in patients with severe liver disease. It is important to discuss all of your medical conditions and medications with your doctor to ensure that the treatment plan is safe and effective for you.

Pregnancy

Safe

Spegra Tablet 90N should only be used in pregnant women if recommended by the doctor after assessing the need and the risk. Your doctor will be able to help you make the best decision for you and your baby's health.

Breastfeeding

Unsafe

It is not recommended to breastfeed while taking Spegra Tablet. It may pass into breast milk and harm the infant. If you are breastfeeding and taking this tablet, it is important to talk to your doctor about the possible risks and benefits of continuing to breastfeed. Your doctor will be able to help you make the best decision for you and your baby's health.

Kidney

Unsafe

Spegra Tablet 90N is not recommended for use in patients with severe kidney disease. It is important to discuss all of your medical conditions and medications with your doctor to ensure that the treatment plan is safe and effective for you.

Quick Tips of Spegra Tablet 90N

• • ​Spegra Tablet 90N is used to treat Human Immunodeficiency Virus (HIV) infection. It helps control HIV infection and prevent the development of acquired immunodeficiency syndrome (AIDS).
  • Take this tablet exactly as prescribed by your doctor. Do not change the dose or stop taking the medication without consulting your doctor.
  • Take this tablet with or without food. It is recommended to take this tablet at the same time every day to ensure a consistent blood level.
    If you experience any side effects from the medication, inform your healthcare provider immediately.
  • Do not miss any dose of Spegra Tablet 90N. If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next dose at the scheduled time.
  • Do not share your antiviral medication with anyone else.
    Spegra Tablet 90N may interact with other medications, so inform your healthcare provider about all the medications you are taking before starting this medication.
  • Before starting treatment with medicine, inform your doctor if you are pregnant, planning on becoming pregnant, or breastfeeding. Also, inform him about your detailed medical history & the medicines and supplements you take.
  • Get regular exercise, which can help strengthen the immune system and improve overall health.

Reference of Spegra Tablet 90N

• 1. Single-dose Fed Bioequivalence Study Of Emtricitabine, Tenofovir Alafenamide And Dolutegravir Tablets (200mg/25mg/50mg) Versus Descovy® Tablets (200mg/25mg; Gilead Sciences) And Tivicay® Tablets (50mg; Viiv Healthcare) In Healthy Adult Volunteers, Authors D. Abhijit1, C. Santanu1, R. Chetan1, G. Sachin1, R. Bangaru2, A.k. Datla2, P. Deshpande3, A. Kanda3, E. Patras3, Available Form 
  

  2. Efficacy And Safety Of Dolutegravir With Emtricitabine And Tenofovir Alafenamide Fumarate Or Tenofovir Disoproxil Fumarate, And Efavirenz, Emtricitabine, And Tenofovir Disoproxil Fumarate Hiv Antiretroviral Therapy Regimens Started In Pregnancy (impact 2010/vested): A Multicentre, Open-label, Randomised, Controlled, Phase 3 Trial, Author- Shahin Lockman Md, Available From 

  3. Dolutegravir, Emtricitabine And Tenofovir Alafenamide Tablets, For Oral Use, Mylan Laboratories Limited, India, Product Leaflet 
  

  4. Dolutegravir With Emtricitabine And Tenofovir Alafenamide Or Tenofovir Disoproxil Fumarate Versus Efavirenz, Emtricitabine, And Tenofovir Disoproxil Fumarate For Initial Treatment Of Hiv-1 Infection (advance): Week 96 Results From A Randomised, Phase 3, Non-inferiority Trial, National Library Of Medicine-NIH, Available Form