Introduction of Spexib 150 mg Capsule

• Spexib 150 mg Capsule belongs to a class of drugs known as anaplastic lymphoma kinase (ALK) inhibitors. Spexib 150 mg Capsule used as monotherapy is indicated for the first-line treatment of adult patients with anaplastic lymphoma kinase (ALK)-positive advanced non-small cell lung cancer (NSCLC). 

  Spexib 150 mg Capsule is not recommended for use in children below 18 years of age due to safety and efficacy have not been established and is advised to be used with caution in elderly patients (aged 65 years and above) after consulting the doctor.
  
  Spexib 150 mg Capsule may cause some common side effects including, increased thirst, urinating often, increased hunger, blurred vision, headaches, tiredness, and breath that smells like fruit. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
  
  Before taking Spexib 150 mg Capsule, you should inform the doctor. If you have any preexisting disease such as kidney disease, liver or heart disease any allergic reactions or any other medical conditions. Please make sure to inform your doctor of all the medicines, including supplements and herbal medicines, you are taking before you start treatment with this Spexib 150 mg Capsule. Spexib 150 mg Capsule is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
  
  ​Spexib 150 mg Capsule can be taken with food or as directed by your doctor. It is best to take the same time every day to improve the clinical condition. In case you miss a dose of Spexib 150 mg take your next dose at your regularly scheduled time. The dose and length of treatment will depend on your condition. Do not stop taking this medicine without consulting your doctor.
  

Uses of Spexib 150 mg Capsule

• ​​​​Non-small cell lung cancer: Spexib 150 mg Capsule is used to treat non-small cell lung cancer, which is a type of lung cancer that affects a large number of cells in the lung. ​
  

Benefits of Spexib 150 mg Capsule

• Non-small cell lung cancer is one of the major kinds of lung cancer and it affects both smokers as well as non-smokers. Spexib 150 mg Capsule helps treat non-small cell lung cancer and may be given alone or in combination with other medicines. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.
  

Side Effects of Spexib 150 mg Capsule

• ​​​​Like all medications, Spexib 150 mg Capsule can cause side effects but do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them.
  

Most Common Side Effects of Spexib 150 mg Capsule

• • Heartburn
  • Constipation
  • Nausea
  • Vomiting
  • Diarrhoea
  • Abdominal pain
  • Loss of appetite
  • Fever
  • Rashes
  • Itching
  • ​Hyperglycemia ( increased sugar)
  • Fainting
  • Seizure​
    

Common Side Effects of Spexib 150 mg Capsule

• • Liver problems ( Nausea/ Vomiting)
  • Tingling/ Numbness
  • Abdominal pain
  • Yellowish skin and eyes
  • Dark urine
  • Blurred vision
  • Decreased vision
  • Generalized weakness
  • Trouble Breathing
  • Difficulty in breathing

How to Use Spexib 150 mg Capsule?

• Spexib 150 mg Capsule should be taken orally once daily with food at the same time every day. Spexib 150 mg should be swallowed whole with water. The capsules should not be chewed or crushed. If a dose is missed, the patient should make up that dose, unless the next dose is due within 12 hours. If vomiting occurs during the course of treatment, the patient should not take an additional dose but should continue with the next scheduled dose. Your doctor will decide on dosage and frequency as per your disease condition and several other factors.
  

How Spexib 150 mg Capsule Works?

• Spexib 150 mg Capsule works by blocking the action of certain abnormal proteins (produced by anaplastic lymphoma kinase defective gene) which helps in preventing the growth of cancer cells and its spread in body thus treating non-small cell lung cancer in affected individuals.
  

Safety Advices Spexib 150 mg Capsule

Breastfeeding

Unsafe

It is not recommended to breastfeed while taking Spexib 150 mg Capsule. Spexib 150 mg may pass into breast milk and harm the infant. If you are breastfeeding and taking Spexib 150 mg Capsule, it is important to talk to your doctor about the possible risks and benefits of continuing to breastfeed. Your doctor will be able to help you make the best decision for you and your baby's health.

Alcohol

Unsafe

It is not recommended to consume alcohol while taking Spexib 150 mg. Alcohol may increase the risk of side effects or interfere with the effectiveness of the Spexib 150 mg Capsule. It is best to talk to your doctor or pharmacist before consuming alcohol while taking any medicine.

Pregnancy

Unsafe

Use of Spexib 150 mg may be unsafe during pregnancy as animal studies indicate that it may harm the developing foetus. However, if you are pregnant or planning to become pregnant, it is important to talk to your doctor about the potential risks and benefits of taking Benefits of Spexib 150 mg Capsule during pregnancy. Your doctor will be able to help you make the best decision for you and your baby's health.

Driving

Unsafe

Spexib 150 mg Capsule may cause blurred vision, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

Use with Caution

Spexib 150 mg Capsule is considered to be safe for use in mild to moderate kidney disease patients. No dose adjustment is necessary in patients with mild to moderate kidney disease patients. Caution should be used in patients with severe kidney disease patients.

Liver

Use with Caution

Spexib 150 mg Capsule is considered to be safe for use in mild to moderate liver disease patients. No dose adjustment is necessary in patients with mild to moderate liver disease patients. For patients with severe liver disease (Child-Pugh C), reduce the dose of Spexib 150 mg.