


Tecentriq 840 mg Injection | 840 mg in 1 Vial

- Manufacturer/Marketed By
Roche Products India Pvt Ltd
- Active Pharmaceutical Ingredient
Atezolizumab 840 mg
(Inclusive of all taxes)
Introduction of Tecentriq 840 mg Injection
Tecentriq 840 mg Injection is an anticancer drug that may be used alone or in combination with other medications for the treatment of various types of cancers related to the lungs, urinary bladder, breast, and liver. Tecentriq 840 mg Injection works by targeting the PD-L1 protein present in some cancer cells, which helps them evade the body's immune system. Blocking the PD-L1 protein, Tecentriq 840 mg allows the immune system to recognize and attack cancer cells, which may slow down or stop the growth of cancer. The use of Tecentriq 840 mg Injection in children or adolescents under the age of 18 years is not recommended, as the safety and efficacy of Tecentriq 840 mg in this population have not been established.
Tecentriq 840 mg Injection can cause common side effects, such as fatigue, nausea, decreased appetite, constipation, cough, and shortness of breath. These side effects may vary in severity and frequency and can be managed with supportive care measures, including lifestyle changes or medications. However, some side effects, such as chest pain, diarrhoea, and dark urine, may indicate more severe complications that require immediate medical attention. It is important to inform your doctor if you experience any side effects while taking Tecentriq 840 mg. They can advise on managing or preventing side effects and monitor the medication's safety and effectiveness.
Before taking Tecentriq 840 mg Injection, it is important to inform your doctor if you have any pre-existing medical conditions such as heart disease, liver or kidney problems, or if you are taking any other medications including prescription drugs, over-the-counter medications, vitamins, and herbal remedies. This Benefits of Tecentriq 840 mg Injection may interact with other medications and cause adverse effects. You should inform your healthcare team of all medications you are currently taking, as they may interact with Tecentriq 840 mg Injection. Your doctor may need to adjust your dosage or monitor you closely for any side effects. If you are pregnant or breastfeeding, the use of Tecentriq 840 mg is not recommended, as it may cause harm to the developing fetus or newborn. Women who are of childbearing age should use effective contraception during treatment to prevent pregnancy.
Tecentriq 840 mg Injection should be administered intravenously by a physician while monitoring blood pressure regularly. The appropriate dosage and frequency of administration will be determined by your doctor based on the severity of your condition and may be subject to change. It is important to follow your doctor's instructions for taking the Tecentriq 840 mg, as taking it improperly or in excess may result in severe adverse effects. Although it may take weeks or months to experience the benefits, do not stop the treatment unless your doctor instructs you to do so.
Uses of Tecentriq 840 mg Injection
Early-stage non-small cell lung cancer: Tecentriq 840 mg Injection used in the treatment of early-stage non-small cell lung cancer (NSCLC) who have undergone resection and platinum-based chemotherapy, the use of Tecentriq 840 mg Injection as a single agent is recommended as an adjuvant treatment if their tumours express PD-L1 on ≥ 1% of tumour cells (TC). This indication is specific to patients with stage II to IIIA, NSCLC. By blocking the PD-L1 protein on cancer cells, Tecentriq 840 mg can activate the immune system to attack and eliminate cancer cells, potentially reducing the risk of cancer recurrence or progression.
Metastatic non-small cell lung cancer: Tecentriq 840 mg Injection is used with a combination of bevacizumab, paclitaxel, and carboplatin and is indicated as a first-line treatment for patients with metastatic non-squamous non-small cell lung cancer.
Small cell lung cancer: Tecentriq 840 mg Injection is used with carboplatin and etoposide and is indicated for the first-line treatment of patients with extensive-stage small cell lung cancer.
Urothelial carcinoma: Tecentriq 840 mg Injection is used in the treatment of urothelial carcinoma, also known as transitional cell carcinoma, is a type of cancer that starts in the urothelial cells, which are the cells that line the urinary tract, including the bladder, ureters, and parts of the kidneys. The most common symptom is blood in the urine, which may be visible or detected through a urine test. Other symptoms may include pain during urination, frequent urination, or urinary urgency.
Triple-negative breast cancer (TNBC): Tecentriq 840 mg Injection used to treat Triple-negative breast cancer, is a type of breast cancer in which the cancer cells do not express the three most common receptors found in breast cancer cells: estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2). This means that Triple-negative cancer is not responsive to hormonal therapies or treatments targeting the HER2 receptor, making it more challenging to treat than other types of breast cancer.
Hepatocellular carcinoma: Tecentriq 840 mg Injection is used with a combination of bevacizumab and is indicated for the treatment of patients with unresectable hepatocellular carcinoma (HCC) who have not received prior systemic therapy. Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer, which means it originates in the liver itself rather than spreading to the liver from other parts of the body. The symptoms may include abdominal pain, swelling or bloating, jaundice, loss of appetite, weight loss, and fatigue.
Benefits of Tecentriq 840 mg Injection
Tecentriq 840 mg Injection is an immunotherapy drug that activates the body's immune system to fight cancer cells. It is used to treat various types of cancer, including lung cancer, bladder cancer, triple-negative breast cancer, and liver cancer. Tecentriq 840 mg Injection has been shown to improve overall immunity and survival in advanced-stage non-small cell lung cancer, triple-negative breast cancer, and bladder cancer. Compared to other anticancer medicines, Tecentriq 840 mg Injection is associated with very few side effects. It is important to note that the specific benefits of Tecentriq 840 mg Injection may vary depending on the type and stage of the cancer being treated, as well as the individual patient's overall health and medical history. Therefore, it is essential to discuss the potential benefits and risks of Tecentriq 840 mg with a doctor before starting treatment.
Side Effects of Tecentriq 840 mg Injection
Like all medications, Tecentriq 840 mg Injection can cause side effects but do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them.
Most Common Side Effects of Tecentriq 840 mg Injection
- Nausea
- Constipation
- Breathlessness
- Decreased Appetite
- Coughing
Common Side Effects of Tecentriq 840 mg Injection
- Black and Tarry Stools
- Fever
- Pain in Bladder
- Breathing Difficulty
- Diarrhoea
- Hair Loss
How to Use Tecentriq 840 mg Injection?
Tecentriq 840 mg Injection is an intravenous infusion, Administered by a healthcare professional or nurse in a hospital or clinic setting. The specific dosing and administration of the Tecentriq 840 mg Injection will be determined by the patient's clinical condition, age, medical history, type of cancer and other factors. It is important to note that this Tecentriq 840 mg should not be self-administered, and it is important to follow the instructions of the healthcare professional administering the Tecentriq 840 mg.
How Tecentriq 840 mg Injection Works?
Tecentriq 840 mg Injection is a monoclonal antibody that blocks the activity of a protein found on T-cells, which are white blood cells that regulate the immune system. By blocking this protein, Tecentriq 840 mg Injection restores the T-cells' ability to kill cancer cells and stimulates the immune system to locate and destroy cancer cells. This mechanism of action makes Tecentriq 840 mg an effective treatment option for certain types of cancer.
Safety Advices Tecentriq 840 mg Injection

Breastfeeding
Unsafe
It is not recommended to breastfeed while taking Tecentriq 840 mg Injection. Tecentriq 840 mg may pass into breast milk and harm the infant. If you are breastfeeding and taking Tecentriq 840 mg Injection, it is essential to talk to your doctor about the possible risks and benefits of continuing to breastfeed. Your doctor can help you make the best decision for you and your baby's health.

Driving
Safe
Tecentriq 840 mg Injection is unlikely to affect your ability to drive or operate machinery. If you experience any side effects while taking Tecentriq 840 mg such as dizziness or drowsiness, it is important to avoid driving or operating heavy machinery until the side effects have resolved.

Kidney
Use with Caution
Tecentriq 840 mg Injection should be used with caution in patients with Kidney disease. It is important that patients with kidney disease closely monitor kidney function while taking Tecentriq 840 mg and report any unusual symptoms or changes in kidney function to their doctor. The dose of Tecentriq 840 mg Injection may need to be adjusted in patients with kidney disease.

Pregnancy
Unsafe
Use of Tecentriq 840 mg Injection may be unsafe during pregnancy as animal studies indicate that it may harm the developing fetus. However, if you are pregnant or planning to become pregnant, it is important to talk to your doctor about the potential risks and benefits of taking Tecentriq 840 mg during pregnancy. Your doctor will be able to help you make the best decision for you and your baby's health.

Alcohol
Unsafe
It is generally not recommended to drink alcohol while taking Tecentriq 840 mg Injection. It may increase the risk of liver damage. It is best to avoid alcohol or limit your alcohol consumption while taking any medication.

Liver
Use with Caution
Tecentriq 840 mg Injection should be used with caution in patients with liver disease. It is important that patients with liver disease closely monitor liver function while taking Tecentriq 840 mg Injection and report any unusual symptoms or changes in liver function to their doctor. The dose of Benefits of Tecentriq 840 mg Injection may need to be adjusted in patients with liver disease.
Anti-Cancer
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