Introduction of Votrient 200 mg Tablet

• Votrient 200 mg Tablet belongs to a class of drugs called tyrosine kinase inhibitors. Votrient 200 mg is used to treat patients with kidney cancer and soft tissue sarcoma (STS), (a type of cancer that develops in the soft tissues of the body, such as muscles, tendons and fat). The safety and efficacy of this medicine in children aged 2 to 18 years have not been established.
  
  Votrient 200 mg Tablet may cause a number of common side effects. These include nausea, vomiting, diarrhoea, abdominal discomfort, decreased appetite, weight loss, difficulty breathing, tumour-related discomfort, bone pain, muscle pain, headache, fatigue, changes in hair or skin colour, or changes in taste. The majority of these side effects will usually go away on their own and do not require immediate medical attention. However, if they continue or get worse, you should contact your doctor or health care professional.
  
  You should not take Votrient 200 mg if you are allergic to pazopanib or any of the ingredients in Votrient 200 Tablet. Before starting treatment, it is important to tell your doctor about any medical conditions such as kidney, heart, lung, liver, bleeding, gastrointestinal, or thyroid problems. It's important to know that regular blood pressure checks are a necessary part of treatment as this tablet may increase your blood pressure. No dose adjustment is usually needed in patients with kidney disease.
  
  Votrient 200 mg Tablet is to be taken orally once a day, preferably without food (at least 1 hour before or 2 hours after a meal), until disease progression is seen. It's important to take this medicine at the same time each day to maximise its effectiveness. Your doctor will determine the appropriate dosage and frequency of dosing based on your specific condition, and this may change over time. It's very important that you follow your doctor's instructions exactly as not taking this medicine properly or taking more than the recommended dose may cause serious side effects. Please be aware that it may take several weeks or months before you start to feel the therapeutic benefits of this medicine, so it's important not to stop taking it unless you are told to do so by your doctor.
  

Uses of Votrient 200 mg Tablet

• • Kidney cancer
  • Soft tissue sarcoma

Benefits of Votrient 200 mg Tablet

• Kidney cancer, also known as renal cancer, is a type of cancer that begins in the kidneys, which are vital organs responsible for filtering waste products and excess fluids from the blood, producing urine, and maintaining the overall functions of the body. Votrient Tablet can stop cancer from growing and prevent cancer cells from multiplying. This helps to stop cancer from spreading to other unaffected areas. You will need to follow your doctor's instructions very carefully to help you recover. 
  

  Soft tissue sarcoma: This is a rare form of cancer which starts in the soft parts of the body. These include muscle, sinew, fat, vascular and nervous tissue. Votrient Tablet works by killing or stopping the growth of cancer cells and by preventing the cancer cells from multiplying. If any of the side effects bother you, tell your doctor or health care professional.
  

Side Effects of Votrient 200 mg Tablet

• ​​​Like all medicines, Votrient 200 mg Tablet may cause side effects which do not require medical attention and which will disappear as your body adjusts to the medicine. Tell your doctor if they persist or if you're worried about them.
  

Most Common Side Effects of Votrient 200 mg Tablet

• • Stomach pain
  • Loss of appetite
  • Nausea
  • Vomiting
  • Diarrhea
  • Weight loss
  • Headache
  • Loss of taste
  • Sore mouth
  • Lack of energy
  • Changes in hair colour
  • Unusual hair loss
  • Skin rash
  • Headache
  • Shortage of breath
  • Bone, muscle and joint pain

Common Side Effects of Votrient 200 mg Tablet

• • Swelling of the brain
  • Sudden and severe rise in BP
  • Increased risk of heart diseases
  • Bleeding in the digestive system
  • Liver problems
  • Blood clots
  • Tumor pain
  • Blurry vision
  • Lung disorders

How to Use Votrient 200 mg Tablet?

• Votrient 200 mg Tablet can be taken orally once a day, preferably without food (at least 1 hour before or 2 hours after a meal). It is recommended that you swallow the tablet whole with a full glass of water and that you do not crush, chew or break the tablet. If you miss a dose of this medicine, take it as soon as you can. Skip the missed dose and return to your regular dosing schedule if it is almost time for your next dose. Do not take a double dose of your medicine to make up for a missed dose.
  

How Votrient 200 mg Tablet Works?

• ​​Votrient 200 mg Tablet belongs to a class of drugs called tyrosine kinase inhibitors, Votrient Tablet works by inhibiting the activity of specific proteins called tyrosine kinases, which play a role in the growth and survival of cancer cells. It inhibits the activity of the BCR-ABL tyrosine kinase, which is a key driver of the abnormal growth of CML and Ph+ ALL cells. By inhibiting the activity of the BCR-ABL tyrosine kinase, Votrient 200 mg can help to slow down or stop the growth and spread of cancer cells, leading to an improvement in symptoms and potential benefits.
  

Safety Advices Votrient 200 mg Tablet

Liver

Use with Caution

For patients with mild liver disease, Votrient 200 mg Tablet is recommended. No dose adjustment is required in patients with mild liver impairment. However, Votrient 200 mg is not recommended for use in patients with moderate or severe liver disease.

Kidney

Safe

For patients with kidney impairment, dose adjustment is not recommended. Votrient 200 Tablet has not been studied in patients with severe renal impairment or in patients who are undergoing peritoneal dialysis or haemodialysis.

Pregnancy

Unsafe

The use of Votrient 200 mg Tablet is not recommended in pregnant women as it may cause harm to the foetus if administered to a pregnant woman.

Driving

Safe

Votrient 200 mg Tablet does not alter or impair the ability to drive or use machines.

Alcohol

Unsafe

Drinking alcohol while taking Votrient 200 mg is generally not recommended. It may increase the risk of liver damage and it is best to avoid alcohol or to limit the amount of alcohol you drink while you are taking this medicine.

Breastfeeding

Unsafe

There are no data on the presence of Votrient 200 mg or its metabolites in human milk or effects on nursing infants or lactation. Because of the potential for serious adverse reactions in nursing infants, women should be advised not to breastfeed during treatment with Votrient 200 Tablet and for 2 weeks after the last dose.