Introduction of Yondelis Injection

• Yondelis Injection is an anti-cancer drug, it is part of a class of drugs called alkylating agents. Yondelis Injection is used to treat advanced soft tissue sarcoma (STS) in patients who have previously received chemotherapy, including regimens containing anthracyclines. It is also used with other medicines to treat relapsed platinum-sensitive ovarian cancer. Yondelis Injection works by attaching to and damaging cellular DNA. This stops the cancer cells from being able to grow and multiply.

  Some common side effects of Yondelis Injection may include headache, fatigue, vomiting, weakness, nausea, increased liver enzymes, low blood platelets, increased creatine phosphokinase level in the blood, decreased white blood cell count (neutrophils), decreased appetite, constipation. This medicine can increase your susceptibility to infection by decreasing the number of blood cells in your blood (decrease in red and white blood cells). You will need regular blood checks to monitor your blood cell count as well as your heart, liver and kidney function. While you are taking this medicine, you should generally avoid drinking alcohol.

  Tell your doctor if you have heart disease, liver or kidney problems, or are taking medicines for infections. Yondelis Injection is not recommended for use during pregnancy or while breast-feeding. Many other medicines may interact with this medicine or be affected by it, so tell your doctor or health care professional about all the medicines you are using. To avoid pregnancy it is important for both men and women to use effective contraception during treatment.

  Yondelis Injection is given as an injection under the supervision of a doctor or nurse. Your doctor will decide what dose is needed and how often you need to take it. This will depend on what you are being treated for, and it may need to be changed from time to time. You should take it exactly as advised by your doctor. If you take it in the wrong way, or if you take too much, you may get very serious side effects. You should not stop taking this medicine unless your doctor tells you to. It may take several weeks or months before you see or feel the benefits of this medicine.
  

Uses of Yondelis Injection

• • Soft tissue sarcoma
  • Ovarian cancer
  • Metastatic liposarcoma

Benefits of Yondelis Injection

• Soft tissue sarcoma: Soft tissue sarcoma is a type of sarcoma that develops in tissue such as bone and muscle. Yondelis Injection works by killing or stopping the growth of cancer cells and preventing cancer cells from multiplying. Tell your doctor or health care professional if you feel any discomfort.

  Ovarian cancer: Ovarian cancer is a type of cancer that begins in the ovaries, which are the female reproductive organs that produce eggs. Yondelis Injection works by killing or stopping the growth of cancer cells and preventing cancer cells from multiplying. Tell your doctor or health care professional if you feel any discomfort.

  Metastatic liposarcoma: Metastatic liposarcoma is an advanced stage of liposarcoma, a type of soft tissue cancer that originates in fat cells. Yondelis Injection works by killing or stopping the growth of cancer cells and preventing cancer cells from multiplying. Tell your doctor or health care professional if you feel any discomfort.
  

Side Effects of Yondelis Injection

• ​​​​​​​​​​​As with all medicines, Yondelis Injection may cause side effects which do not require medical attention and which will disappear as your body adjusts to the medicine. If they persist or you're concerned about them, tell your doctor.​​
  

Most Common Side Effects of Yondelis Injection

• • Constipation
  • Decreased appetite
  • Breathlessness
  • Headache
  • Anemia
  • Decreased RBC and platelet counts
  • Nose bleeding
  • Pain in the back and joints
  • Sleeping problems
  • Hair loss
  • Headache

Common Side Effects of Yondelis Injection

• • Fever
  • Nausea, vomiting
  • Decreased urination
  • Severe muscle pain
  • Severe allergic reactions

How to Use Yondelis Injection?

• This Yondelis Injection is administered by a qualified health care professional. Do not self-medicate with this Yondelis Injection. Dosage and frequency will be determined by your doctor according to your medical condition and several other factors.
  

How Yondelis Injection Works?

• Yondelis Injection is in a class of drugs known as alkylating agents. It works by attaching to and damaging cell DNA. This stops the cancer cells from being able to grow and multiply.
  

Safety Advices Yondelis Injection

Pregnancy

Unsafe

Use of Yondelis Injection may be unsafe during pregnancy as animal studies indicate that it may harm the developing foetus. However, if you are pregnant or planning to become pregnant, it is important to talk to your doctor about the potential risks and benefits of taking Yondelis Injection during pregnancy. Your doctor will be able to help you make the best decision for you and your baby's health.

Alcohol

Unsafe

It is generally not recommended to drink alcohol while taking Yondelis Injection. It may increase the risk of liver damage. it is best to avoid alcohol or limit your alcohol consumption while taking any medication.

Driving

Unsafe

Yondelis Injection may cause dizziness, fatigue, and difficulty concentrating and coordinating, which may affect your ability to drive a vehicle safely. It is important to follow your doctor's instructions and take necessary precautions such as avoiding driving a vehicle or operating heavy machinery if you suffer from the side effects of this Yondelis Injection.

Liver

Use with Caution

Yondelis Injection should be used with caution in patients with liver disease. It is important that patients with liver disease closely monitor liver function while taking Yondelis Injection and report any unusual symptoms or changes in liver function to their doctor. The dose of Yondelis Injection may need to be adjusted in patients with liver disease.

Breastfeeding

Unsafe

It is not known whether Yondelis Injection passes into breast milk. If you are breastfeeding and taking Yondelis Injection it is important to talk to your doctor about the potential risks and benefits of continuing to breastfeed. Your doctor will be able to help you make the best decision for you and your baby's health.

Kidney

Use with Caution

Yondelis Injection should be used with caution in patients with kidney disease. It is important that patients with kidney disease closely monitor kidney function while taking Yondelis Injection and report any unusual symptoms or changes in kidney function to their doctor. Your doctor may need to be adjusted the dose in such kidney disease patients.