Introduction of Zynesp 40 mcg Injection

• ​Zynesp 40 mcg PFS is an erythropoiesis-stimulating agent. Zynesp 40 mcg PFS is used in the treatment of anaemia due to chronic kidney disease and anaemia due to chemotherapy. Zynesp 40 mcg PFS works by stimulating the bone marrow (soft tissue inside the bones which produces red blood cells) to produce more red blood cells.
  
  ​Zynesp 40 mcg PFS may cause some common adverse effects including low blood pressure, cough, trouble breathing, stomach pain, and swelling in your arms or legs. However, Zynesp 40 mcg PFS may also lead to more severe side effects, such as headache, unusual weakness or tiredness, seizure (convulsions), shortness of breath, swelling, and rapid weight gain. Please inform your doctor as these are the most frequently reported side effects. Your doctor may be able to provide suggestions for reducing or preventing these side effects.
  
  ​Using Zynesp 40 mcg PFS may increase the chance of severe heart or circulation issues, such as stroke or heart attack, which can be life-threatening. if you notice any symptoms such as chest pain, shortness of breath, sudden numbness or weakness, confusion, vision or balance problems, difficulty speaking or understanding, or pain or coldness in an arm or leg, you should discontinue the use of Zynesp 40 mcg PFS and seek immediate medical attention from a doctor.
  
  ​Before taking Zynesp 40 mcg PFS, you should inform your doctor of any pre-existing medical conditions, such as uncontrolled blood pressure, heart disease, liver or kidney problems, seizures, blood clots problems or if you are currently taking any other medications, including prescription drugs, over-the-counter medications, vitamins, and herbal remedies. This is because Zynesp 40 mcg PFS may interact with other medications and result in adverse effects. Your doctor may need to adjust your dosage or closely monitor you for any side effects.
  
  ​Zynesp 40 mcg PFS can be administered under the skin or infusion into a vein. Your doctor will decide the appropriate dose and frequency of administration based on the severity of your condition, which may change over time. It is important to follow your doctor's instructions for taking Zynesp 40 mcg PFS, as taking the wrong dose or taking too much may result in severe adverse effects. Even though it may take several weeks or months to observe the benefits of the Zynesp 40 mcg PFS, you may need to undergo frequent medical tests to ensure that the medication is not causing any harmful effects.​
  

Uses of Zynesp 40 mcg Injection

• Treatment of symptomatic anaemia associated with chronic renal failure (CRF): Zynesp 40 mcg PFS is used in the treatment of symptomatic anaemia associated with chronic renal failure (CRF) in adults and paediatric patients, including patients on dialysis and patients not on dialysis.
  
  Treatment of Anemia due to cancer chemotherapy: Zynesp 40 mcg PFS is used in the treatment of anaemia in adult cancer patients with non-myeloid malignancies receiving chemotherapy.
  

Benefits of Zynesp 40 mcg Injection

• ​Treatment of Anemia due to chronic kidney disease: Anemia is a condition where your body does not have enough red blood cells to carry oxygen around your body. Chronic kidney disease (CKD) refers to the loss of normal kidney function over a long span of time. CKD progresses gradually over a few years but may become permanent if left untreated. CKD can lead to anaemia. Zynesp 40 mcg PFS can boost your levels of red blood cells and reduce the symptoms of anaemia such as tiredness and weakness. Taking this injection improves the quality of life.
  
  ​Treatment of Anemia due to cancer chemotherapy: Anemia caused by cancer chemotherapy is a common side effect of cancer treatment that occurs when the chemotherapy drugs damage or destroy the bone marrow cells responsible for producing red blood cells. This can lead to a decrease in the number of red blood cells, resulting in symptoms such as fatigue, weakness, shortness of breath, and dizziness. Zynesp 40 mcg PFS may help the body produce more red blood cells. Iron supplements may also be recommended to support the production of healthy red blood cells. In addition, maintaining lifestyle changes such as a healthy diet, regular exercise, and quitting smoking may also be recommended to manage anaemia caused by chemotherapy. Close monitoring of vitals and regular blood tests are also essential in managing anaemia and preventing complications associated with chemotherapy.​
  

Side Effects of Zynesp 40 mcg Injection

• ​​Like all medications, Zynesp 40 mcg PFS can cause side effects but do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them.​
  

Most Common Side Effects of Zynesp 40 mcg Injection

• • High blood pressure
  • Fluid retention
  • Anxiety
  • Difficulty with speaking (slow speech or unable to speak)
  • Double vision
  • Seizures
  • Trouble with thinking
  • Trouble with walking​

Common Side Effects of Zynesp 40 mcg Injection

• • Blood clots
  • Headache
  • Pain in the injected site
  • Joint pain
  • Chills
  • Confusion
  • Cough producing mucus
  • Decrease in the amount of urine
  • Diarrhoea
    
  • Pounding in the ears
  • Rapid breathing
  • Rapid or pounding pulse
  • Skin discolouration at the injection site
  • Stomach pain
    

How to Use Zynesp 40 mcg Injection?

• ​​Zynesp 40 mcg PFS is administered by a healthcare professional or nurse in a hospital or clinic setting. The specific dosing and administration of Zynesp 40 mcg PFS will depend on the clinical condition of the patient's age and medical history, and other factors. Kindly do not self-administer.​
  

How Zynesp 40 mcg Injection Works?

• Zynesp 40 mcg PFS is a synthetic form of the hormone erythropoietin, which is produced naturally by the body. {Produtc_name} works by mimicking the action of erythropoietin and stimulating the production of red blood cells in the bone marrow. It does this by binding to erythropoietin receptors on the surface of bone marrow cells called erythroblasts. When Zynesp 40 mcg PFS binds to these receptors, it activates a series of signalling pathways within the erythroblasts that lead to the production of more red blood cells.​​ ​ ​ ​ ​​ ​ ​
  

Safety Advices Zynesp 40 mcg Injection

Driving

Safe

Zynesp 40 mcg PFS should not affect your ability to drive or use machinery.

Breastfeeding

Unsafe

It is not recommended to breastfeed while taking Zynesp 40 mcg PFS. Zynesp 40 mcg PFS may pass into breast milk and harm the infant. If you are breastfeeding and taking Zynesp 40 mcg, it is important to talk to your doctor about the possible risks and benefits of continuing to breastfeed. Your doctor will be able to help you make the best decision for you and your baby's health.

Alcohol

Unsafe

It is generally not recommended to drink alcohol while taking Zynesp 40 mcg PFS. It may increase the risk of liver damage. it is best to avoid alcohol or limit your alcohol consumption while taking any medication.

Pregnancy

Unsafe

Use of Zynesp 40 mcg PFS may be unsafe during pregnancy as limited animal studies indicate that it may harm the developing foetus. However, if you are pregnant or planning to become pregnant, it is important to talk to your doctor about the potential risks and benefits of taking Zynesp 40 mcg during pregnancy. Your doctor will be able to help you make the best decision for you and your baby's health.

Kidney

Safe

Zynesp 40 mcg PFS is safe to use in patients with kidney disease. No dose adjustment of Zynesp 40 mcg is recommended. If you experience any side effects please consult your doctor.

Liver

Use with Caution

Zynesp 40 mcg PFS should be used with caution in patients with liver disease. It is important that patients with liver disease closely monitor liver function while taking Zynesp 40 mcg and report any unusual symptoms or changes in liver function to their doctor. The dose of Side effects of Zynesp 40 mcg PFS may need to be adjusted in patients with liver disease.