Introduction of Jakavi 20 mg Tablet

• Jakavi 20 mg Tablet is a Janus kinase inhibitor. It is used for the treatment of intermediate or high-risk Myelofibrosis (an uncommon type of bone marrow cancer) and Polycythemia Vera (a blood disorder characterized by an overproduction of red blood cells). A blood cell count must be performed before initiating therapy withJakavi 20 Tablet. Jakavi 20 mg Tablet is not recommended for use in patients under 12 years of age safety and efficacy are not established.

  Common side effects include bruising, dizziness, headache, urinary infections, weight gain and bloating. These side effects may be temporary and in most cases will go away on their own. However, if they continue or get worse, tell your doctor or health care professional. This medicine can decrease the number of blood cells in your blood (decrease in red blood cells), which can increase your susceptibility to infection. You will need regular blood checks to monitor your blood counts as well as your heart, liver, kidney, and lipid levels.

  Jakavi 20 mg Tablet is not recommended for during pregnancy while planning to become pregnant, or while breastfeeding, as it may cause birth defects and abortion. Please consult your doctor before taking Jakavi 20 mg. Please make sure to inform your doctor, if you have any signs of infection or if you have any pre-existing disease such as kidney or liver disease or any other health problems before taking this medicine. Additionally, let your doctor know about any other medications you are taking, as they may interact with Jakavi 20 Tablet. Regular blood tests will be conducted to monitor the number of blood cells, sugar levels and cholesterol levels in your blood.

  You can take Jakavi 20 mg Tablet with or without food or as directed by your doctor. Take it at the same time each day. Take this medication with the aid of using your mouth with a pitcher of water. Do not break, crush, chew or open the tablet. If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and take your usual dose.

Uses of Jakavi 20 mg Tablet

• Polycythemia vera: Jakavi 20 mg Tablet treats polycythemia vera, a rare blood disorder in which the body produces too many red blood cells. The excess red blood cells can cause the blood to become thick and sticky, making it more difficult to flow through the blood vessels. This can lead to several complications, including an increased risk of blood clots that can cause a heart attack or stroke.

  Chronic idiopathic myelofibrosis: Jakavi 20 mg Tablet is used to treat chronic idiopathic myelofibrosis (also called primary myelofibrosis), a type of bone marrow disease in which the bone marrow is replaced by scar tissue, leading to a reduction in the production of blood cells. The scar tissue can also cause excess fluid to build up in the abdomen (ascites) and fat cells to build up in the liver and spleen.

Benefits of Jakavi 20 mg Tablet

• Jakavi 20 mg Tablet can be effective in reducing symptoms associated with myelofibrosis, such as fatigue, enlarged spleen, and uncontrolled bleeding

  Jakavi 20 Tablet may improve the overall quality of life and reduce the symptoms of myelofibrosis.

  Jakavi 20 mg Tablet has been shown to reduce bone marrow fibrosis (scarring) in those with myelofibrosis.
  
  Jakavi 20 mg Tablet prevent cancer in those with myelofibrosis and helps to prevent the progression of myelofibrosis to acute myeloid leukaemia (AML

Side Effects of Jakavi 20 mg Tablet

• ​Like all medicines, Jakavi 20 Tablet may have side effects. If you experience any, contacting your doctor or healthcare provider as soon as possible is important. They may be able to offer strategies to help manage or reduce the severity of these side effects.

Most Common Side Effects of Jakavi 20 mg Tablet

• • Headache
  • dizziness
  • Weight gain
  • High blood pressure
  • High cholesterol
  • Flatulence
  • Abnormal liver function tests
  • Difficulty in breathing
  • Constipation

Common Side Effects of Jakavi 20 mg Tablet

• • Decrease in red blood cells
    
  • Infection

How to Use Jakavi 20 mg Tablet?

• You can take Jakavi 20 mg with or without food. Make sure that you take it at the same time of the day every day. Swallow the pill entirely with a drink of water. Do not crush, chew or open the tablet. If you miss a dose of this medicine, take it as soon as you remember to do so. Skip the missed dose and resume your regular dosing schedule if it's almost time for your next dose. To make up for a missed dose, do not take two doses at once.
  

How Jakavi 20 mg Tablet Works?

• Jakavi 20 mg Tablet belongs to a class of drugs known as Janus kinase inhibitors (JAKs). It works by inhibiting the activity of certain proteins called JAKs, which play a role in signalling pathways that regulate the production of certain proteins in the body. By inhibiting these proteins, Jakavi 20 Tablet may help to reduce inflammation and improve symptoms in certain diseases such as myelofibrosis and polycythemia vera.
  

Safety Advices Jakavi 20 mg Tablet

Driving

Unsafe

Using Jakavi 20 mg Tablet may cause dizziness, fatigue, and problems with concentration or coordination, which may affect your ability to drive safely. It's important to follow your doctor's advice and take the necessary precautions, such as not driving or operating heavy machinery, if you experience these side effects from Jakavi 20 Tablet.

Alcohol

Unsafe

It's a good idea to avoid drinking alcohol while taking Jakavi 20 mg Tablet. Alcohol may increase the risk of side effects or decrease the effectiveness of Jakavi 20 mg. For your safety, consult your doctor or pharmacist before mixing alcohol with any medication.

Kidney

Use with Caution

Patients with kidney disease should use Jakavi 20 mg Tablet with caution. It's important for these patients to monitor their kidney function regularly while taking Jakavi 20 mg and to report any unusual symptoms or changes to their healthcare provider immediately. Dosage adjustments for Jakavi 20 Tablet may be necessary in individuals with kidney disease.

Breastfeeding

Unsafe

Breastfeeding while using Jakavi 20 mg Tablet is generally not recommended as Jakavi 20 Tablet can pass into breast milk and potentially harm your baby. If you're currently breastfeeding and using Jakavi 20 mg, it's important to consult your doctor. They can discuss the potential risks and benefits with you and help you make the best choice for you and your baby.

Pregnancy

Unsafe

Using Jakavi 20 mg Tablet during pregnancy may be risky as animal studies have shown that it may have adverse effects on the developing foetus. If you are pregnant or planning to become pregnant, it is important to discuss the potential risks and benefits of taking Jakavi 20 Tablet with your doctor. Your doctor can help you make the best decision for your health and the health of your baby.

Liver

Use with Caution

Patients with liver disease should use Jakavi 20 mg Tablet cautiously. It's important for these people to monitor their liver function regularly while using Jakavi 20 Tablet and to tell their doctor immediately of any unusual symptoms or changes. The dose of Jakavi 20 mg may need to be adjusted in people with liver disease.