Introduction of Posatral Tablet

• Posatral Tablet is used to prevent certain fungal infections in patients who have a severely weakened immune system (patients who have had chemotherapy) and belongs to a class of medicines called antifungals.  Posatral 100 mg Tablet works by stopping the growth of fungi. This medicine is indicated for the prevention of invasive fungal infections in patients with neutropenia or haematopoietic stem cell transplant recipients receiving high-dose immunosuppressive therapy for graft-versus-host disease, and for the treatment of fungal infections.

  Some common side effects of Posatral Tablet include diarrhoea, nausea, fever, vomiting, headache, cough and low blood potassium. Most of these side effects of Posatral 100 mg Tablet do not require medical attention and will gradually resolve over time, but if they persist or worsen, seek advice from your doctor.

  Tell your doctor if you are allergic or hypersensitive to any of the ingredients in Posatral Tablet, or if you are pregnant, suspect you may be pregnant, plan to become pregnant or are breastfeeding; your doctor will only prescribe Posatral Tablet if the benefits outweigh the risks. Before taking this medicine, tell your doctor about your medical history and current therapies to rule out any possible adverse effects or interactions.

  Posatral Tablet is contraindicated in individuals with known hypersensitivity or allergy to other antifungal drugs such as ketoconazole, fluconazole, itraconazole or voriconazole. Before taking Posatral Tablet it's necessary to consult your doctor if you have certain heart conditions such as abnormal heart rhythm (long QTc interval), weakness of the heart muscle, heart failure or any heart rhythm disturbances, or if you experience severe kidney problems, diarrhoea or vomiting while being treated with this medicine, it's important to tell your doctor immediately as these conditions may affect the medicine's ability to work.

  Take Posatral Tablet exactly as prescribed by your doctor. This medicine is usually taken by mouth with or without a full meal. Do not cut, crush, chunk or open this medicine. Your doctor will decide how much of this medicine to take and how long to keep taking it, based on your age, weight and medical condition. Do not stop taking your medicine unless your doctor or health care professional tells you.
  

Uses of Posatral Tablet

• • Fungal infections
  • Prophylaxis of invasive Aspergillus and Candida infections in severely immunocompromised patients.
    

Benefits of Posatral Tablet

• Posatral Tablet is an antifungal drug contained in Posaconazol. It is used to treat fungal infections in adults. It is also indicated for the prevention of invasive Aspergillus and Candida infections in patients who are severely immunocompromised and at high risk of developing these infections, such as haematopoietic stem cell transplant (HSCT) recipients with graft-versus-host disease (GVHD) or patients with haematological malignancies with prolonged neutropenia from chemotherapy.
  

Side Effects of Posatral Tablet

• ​Like any medication, Posatral Tablet can have some side effects. You should tell your doctor or health care professional as soon as possible if you experience any of these side effects. Your doctor may be able to suggest ways to manage or reduce these side effects.​
  

Most Common Side Effects of Posatral Tablet

• • Itching
  • Fever
  • Diarrhoea
  • Weakness
  • Vomiting
  • Heartburn
  • Cough
  • Sore throat
  • Nose bleeds
  • Increased sweating
  • Sores on lips, mouth or throat
  • Sleeplessness
  • ​Swelling of hands
  • Headache
  • Chills
  • Dizziness
  • Constipation
  • Backache
  • Muscle pain
  • Sore throat
    

Common Side Effects of Posatral Tablet

• • Yellowish skin and eyes
  • Dark urine
  • Arrhythmias ( irregular heartbeats)
  • Sudden LOC ( loss of consciousness)
  • Rapid or shortness of breathing
  • Extreme tiredness
  • Bleeding
  • Neutropenia
  • Hypokalemia ( low potassium level)
  • Thrombocytopenia ( low platelets)
  • Thrombophlebitis ( inflammation of a vein due to a blood clot)

How to Use Posatral Tablet?

• Follow your doctor's instructions exactly when taking Posatral Tablet. It is usually taken by mouth with or without food. It is important not to change the shape of the medicine by cutting, crushing or opening. The dosage and duration of treatment will be determined by your doctor, taking into account factors such as your age, weight and medical condition. You mustn't stop taking this medicine unless your doctor or health care professional tells you to.
  

How Posatral Tablet Works?

• Posatral Tablet inhibits the synthesis of ergosterol, a vital fungal cell membrane component. This disruption effectively treats fungal infections by weakening the membrane leading to cell death.
  

Safety Advices Posatral Tablet

Pregnancy

Unsafe

Posatral Tablet may be unsafe to use during pregnancy. Although there is limited research in humans, animal research has proven dangerous results for the growing baby. your doctor will weigh the benefits and any risks before prescribing it to you. Please seek advice from your doctor.

Driving

Unsafe

You may feel dizzy, drowsy, or have blurred vision while taking Posatral 100 mg Tablet which may affect your ability to drive.

Alcohol

Not known

The safety of drinking alcohol with Posatral Tablet is not known and it is recommended that you discuss it with your doctor.

Kidney

Use with Caution

Use cautiously in people with kidney disease/renal impairment. The dosage of Posatral 100 mg Tablet may require modification. It is advisable to seek advice from your doctor. It is recommended to monitor kidney function tests regularly while using this medication. The use of Posatral Tablet may not be suitable for patients with mild to severe kidney disease.

Breastfeeding

Unsafe

Posatral Tablet may be risky to use during the duration of breastfeeding. Limited human information indicates that the drug may also pass into breast milk and harm the baby.

Liver

Use with Caution

Posatral Tablet should be used with caution in patients with liver impairment. The dosage of Posatral 100 mg Tablet may need to be adjusted. It is advisable to seek advice from your doctor. It is recommended to monitor liver function tests regularly while using this medication.