Introduction of Posoxil GR Tablet

• Posoxil GR Tablet is used to prevent certain fungal infections in patients who have a severely weakened immune system (patients who have had chemotherapy) and belongs to a class of medicines called antifungals.  Posoxil GR Tablet works by stopping the growth of fungi. This medicine is indicated for the prevention of invasive fungal infections in patients with neutropenia or haematopoietic stem cell transplant recipients receiving high-dose immunosuppressive therapy for graft-versus-host disease, and for the treatment of fungal infections.

  Some common side effects of Posoxil GR Tablet include diarrhoea, nausea, fever, vomiting, headache, cough and low blood potassium. Most of these side effects of Posoxil GR Tablet do not require medical attention and will gradually resolve over time, but if they persist or worsen, seek advice from your doctor.

  Tell your doctor if you are allergic or hypersensitive to any of the ingredients in Posoxil GR Tablet, or if you are pregnant, suspect you may be pregnant, plan to become pregnant or are breastfeeding; your doctor will only prescribe Posoxil GR Tablet if the benefits outweigh the risks. Before taking this medicine, tell your doctor about your medical history and current therapies to rule out any possible adverse effects or interactions.

  Posoxil GR Tablet is contraindicated in individuals with known hypersensitivity or allergy to other antifungal drugs such as ketoconazole, fluconazole, itraconazole or voriconazole. Before taking Posoxil GR Tablet it's necessary to consult your doctor if you have certain heart conditions such as abnormal heart rhythm (long QTc interval), weakness of the heart muscle, heart failure or any heart rhythm disturbances, or if you experience severe kidney problems, diarrhoea or vomiting while being treated with this medicine, it's important to tell your doctor immediately as these conditions may affect the medicine's ability to work.

  Take Posoxil GR Tablet exactly as prescribed by your doctor. This medicine is usually taken by mouth with or without a full meal. Do not cut, crush, chunk or open this medicine. Your doctor will decide how much of this medicine to take and how long to keep taking it, based on your age, weight and medical condition. Do not stop taking your medicine unless your doctor or health care professional tells you.
  

Uses of Posoxil GR Tablet

• • Fungal infections
  • Prophylaxis of invasive Aspergillus and Candida infections in severely immunocompromised patients.
    

Benefits of Posoxil GR Tablet

• Posoxil GR Tablet is an antifungal drug contained in Posaconazol. It is used to treat fungal infections in adults. It is also indicated for the prevention of invasive Aspergillus and Candida infections in patients who are severely immunocompromised and at high risk of developing these infections, such as haematopoietic stem cell transplant (HSCT) recipients with graft-versus-host disease (GVHD) or patients with haematological malignancies with prolonged neutropenia from chemotherapy.
  

Side Effects of Posoxil GR Tablet

• ​Like any medication, Posoxil GR Tablet can have some side effects. You should tell your doctor or health care professional as soon as possible if you experience any of these side effects. Your doctor may be able to suggest ways to manage or reduce these side effects.​
  

Most Common Side Effects of Posoxil GR Tablet

• • Itching
  • Fever
  • Diarrhoea
  • Weakness
  • Vomiting
  • Heartburn
  • Cough
  • Sore throat
  • Nose bleeds
  • Increased sweating
  • Sores on lips, mouth or throat
  • Sleeplessness
  • ​Swelling of hands
  • Headache
  • Chills
  • Dizziness
  • Constipation
  • Backache
  • Muscle pain
  • Sore throat
    

Common Side Effects of Posoxil GR Tablet

• • Yellowish skin and eyes
  • Dark urine
  • Arrhythmias ( irregular heartbeats)
  • Sudden LOC ( loss of consciousness)
  • Rapid or shortness of breathing
  • Extreme tiredness
  • Bleeding
  • Neutropenia
  • Hypokalemia ( low potassium level)
  • Thrombocytopenia ( low platelets)
  • Thrombophlebitis ( inflammation of a vein due to a blood clot)

How to Use Posoxil GR Tablet?

• Follow your doctor's instructions exactly when taking Posoxil GR Tablet. It is usually taken by mouth with or without food. It is important not to change the shape of the medicine by cutting, crushing or opening. The dosage and duration of treatment will be determined by your doctor, taking into account factors such as your age, weight and medical condition. You mustn't stop taking this medicine unless your doctor or health care professional tells you to.
  

How Posoxil GR Tablet Works?

• Posoxil GR Tablet inhibits the synthesis of ergosterol, a vital fungal cell membrane component. This disruption effectively treats fungal infections by weakening the membrane leading to cell death.
  

Safety Advices Posoxil GR Tablet

Pregnancy

Unsafe

Posoxil GR Tablet may be unsafe to use during pregnancy. Although there is limited research in humans, animal research has proven dangerous results for the growing baby. your doctor will weigh the benefits and any risks before prescribing it to you. Please seek advice from your doctor.

Driving

Unsafe

You may feel dizzy, drowsy, or have blurred vision while taking Posoxil GR Tablet which may affect your ability to drive.

Alcohol

Not known

The safety of drinking alcohol with Posoxil GR Tablet is not known and it is recommended that you discuss it with your doctor.

Kidney

Use with Caution

Use cautiously in people with kidney disease/renal impairment. The dosage of Posoxil GR Tablet may require modification. It is advisable to seek advice from your doctor. It is recommended to monitor kidney function tests regularly while using this medication. The use of Posoxil GR Tablet may not be suitable for patients with mild to severe kidney disease.

Breastfeeding

Unsafe

Posoxil GR Tablet may be risky to use during the duration of breastfeeding. Limited human information indicates that the drug may also pass into breast milk and harm the baby.

Liver

Use with Caution

Posoxil GR Tablet should be used with caution in patients with liver impairment. The dosage of Posoxil GR Tablet may need to be adjusted. It is advisable to seek advice from your doctor. It is recommended to monitor liver function tests regularly while using this medication.